… -binding domain sufficient for sequence-specific recognition of a “GATA… independent on
GATA4 DNA binding to DNA. It was found that the N-terminal and C-terminal activation domains …

… N-finger mutations decreased GATA-2 chromatin occupancy … (A) GATA-2 structural model
based on human GATA-3 … , we asked whether GATA-2 DNA binding activity is inconsequential …

… The DNA binding domain of these GATA transcription factors have been well-… N-terminal
zinc-finger loop. Subfamily V includes OsGATA26 and OsGATA24 with 2 and 3 GATA domains …

… The diagram on the right depicts how an inhibitory GATA-2 C-finger … in which GATA-2–dependent
pathogenesis is independent of … In contrast, GATA-2 N-terminal zinc finger (N-finger) …

… To confirm these observations in an independent cohort, we explored the TCGA data set.
Again… N-terminal zinc-finger domain, which is known to have higher affinity to the “AGATB” DNA …

… of two highly conserved domains, the N-terminal (N-ZnF) and … that functions of SrpNC that
are independent of Ush, are … stability of DNA binding on more complex binding sites. However, …

… mutants interact with the DNA, independent of the presence of the second GATA-type zinc-…
N-terminal zinc-finger is shown to recognize the AGAT[C/G/T] motif and directs DNA binding in …

… Early studies of zinc fingers have been limited to DNA binding ability and its … N-terminal
fingers of chicken GATA-2 and GATA-3 are independent sequencespecific DNA binding domains…

… (plus one adjacent residue on the N-terminal side) of three … one flanking residue on the
N-terminal side) of various GATA … the double zinc finger DNA-binding domain regardless of the …

… been discovered that have an HSC-independent origin (reviewed in [1… is found in the zinc
finger domains, which are about 80% … This combination of DNA sequence-specific binding and …